2013; 4(2): 71-78.Available online at, Revised National Tuberculosis Control Program, http://www.tbfacts.org/tb-statistics-india.html, http://chealth.canoe.ca/channel_condition_info_details.asp?disease_id=231&channel_id=1020&relation_id=71085, "Awakening to Crisis, India Plans New Push Against TB", "India records 2.15m new TB patients in 2018", "The Social Determinants of Tuberculosis: From Evidence to Action", "Resurrecting social infrastructure as a determinant of urban tuberculosis control in Delhi, India", "Revised National Tuberculosis Control Program in India: The Need to Strengthen", "Totally Drug-Resistant Tuberculosis in India", "Nutrition, Diabetes and Tuberculosis in the Epidemiological Transition", "Controlling tuberculosis by sniffing in a vaccine", "History of TB in India - Ancient times until the end of colonial rule", "Totally drug-resistant TB at large in India", "Welcome to the Tuberculosis Association of India", "Fighting TB stigma: we need to apply lessons learnt from HIV activism", "Addressing poverty through disease control programmes: examples from Tuberculosis control in India", "MDR, XDR, TDR tuberculosis: Ominous progression", "A Brief History of Tuberculosis Control in India", Microscopic Observation Drug Susceptibility assay, Campaign for Access to Essential Medicines, The Global Fund to Fight AIDS, Tuberculosis and Malaria, International Union Against Tuberculosis and Lung Disease, Mycobacterium Tuberculosis Structural Genomics Consortium, Phipps Institute for the Study, Treatment and Prevention of Tuberculosis, Ministry of Drinking Water and Sanitation, Ministry of Housing and Urban Poverty Alleviation, https://en.wikipedia.org/w/index.php?title=Tuberculosis_in_India&oldid=982686507, Articles with incomplete citations from August 2018, Articles with dead external links from August 2018, Articles lacking reliable references from August 2018, Creative Commons Attribution-ShareAlike License, This page was last edited on 9 October 2020, at 18:06. Patients are said to have failed treatment if they. The terms "preventive therapy" and "chemoprophylaxis" have been used for decades and are preferred in the UK because it involves giving medication to people who have no active disease and are currently well, the reason for treatment is primarily to prevent people from becoming unwell. [citation needed], Giving vitamin D to TB patients who are vitamin D deficient may be beneficial in a proportion of patients. The most useful drugs (INH and RMP) should be tested first, because the absence of these drugs from a treatment regimen severely impairs its efficacy. Bayer is currently running a phase II clinical trial in collaboration with the TB Alliance to evaluate shorter treatment regimens for TB;[180] encouragingly, Bayer have also promised that if the trials are successful, Bayer will make moxifloxacin affordable and accessible in countries that need it. There are variety of reasons why patients fail to take their medication. [132] From 1983 to 2000, they performed 180 operations in 172 patients; of these, 98 were lobectomies, and 82 were pneumonectomies. (2012). This is incredibly imperative to eliminating tuberculosis because it allows healthcare workers to have follow-up checkups with patients in order to ensure that tuberculosis treatments are effective. The program uses the WHO-recommended Directly Observed Treatment Short Course (DOTS) strategy to develop ideas and data on TB treatment. In addition, they check body fluids. Inactive tuberculosis means that one can even unconsciously and unknowingly acquire the bacteria for tuberculosis within them but not even know about it because it is inactive. chest pain, [21] “In 2010 the RNTCP made a major policy decision that it would change focus and adopt the concept of Universal Access to quality diagnosis and TB treatment for all TB patients”. [medical citation needed], DOTS stands for "Directly Observed Treatment, Short-course" and is a major plank in the World Health Organization (WHO) Global Plan to Stop TB. Steroid treatment in these patients should be considered on a case by case basis by the attending physician. Sputum culture-positive patients who are smear-negative at the start of treatment do well with only 4 months of treatment (this has not been validated for HIV-positive patients); sputum culture-negative patients do well on only 3 months of treatment (possibly because some of these patients never had TB at all). There is a vaccine against some forms of tuberculosis. Please refer to the entry on rifampicin for further details. The antibiotics most commonly used include isoniazid, rifampin, pyrazinamide, and ethambutol. [5][6] A drug may be classed as second-line instead of first-line for one of three possible reasons: it may be less effective than the first-line drugs (e.g., p-aminosalicylic acid); or, it may have toxic side-effects (e.g., cycloserine); or it may be effective, but unavailable in many developing countries (e.g., fluoroquinolones): Third-line drugs (WHO group 5) include drugs that may be useful, but have doubtful or unproven efficacy: These drugs are listed here either because they are not very effective (e.g., clarithromycin) or because their efficacy has not been proven (e.g., linezolid, R207910).
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